Here is a speedbump. Waking up seekers and communities of practice tend to resist academic rigor. The “gift from god” theory of waking up would say it is impossible to study academically because it is the “grace of God” while the practiotioner approach is often guarded by secrecy and gatekeepers. Others are outright illegal such as Ayahuasca, mushrooms and other psychedelics. A side issue is cultural appropriation, which can bring strong protests and even threats of violence such as in Native American sweat lodge or Peyote appropriation.
While It is possible to conduct a comparatuve study of Golden Dawn vs Birkham Yoga vs Church of our Savior of the Third Pentacost - or whatever, then deconstruct the waking up experience and establish “best practices” backed by graphs displaying effort vs measurable physical, psychological and sociological results. I expect such a study would be difficult to carry out, though. But not impossible.
Perhaps it would be easist to begin be comparing those who have already submitted to scientific rigor and claim some degree of scientific basis and repeatable results in their practice such as Wim Hoff, Holosync, Sadhguru, etc. Another one even already involved in Integral
and probably very approachable is Doshi of “Integral Zen”
“Cleaning Up” has a different problem in that the Departments of Psychology have exclusive control over “Therapy” and in most places it is illegal to help others “clean up” uless you can say it is exclusively for “vocational and general self improvement purposes” and not " deep work". For example, if “coaching” a person through hypnotism, shadow work, or other processes, as soon as you come across any “symptom” that may indicate a condition described in the DSM-5, you are treading in dangerous legal waters.
The summary being that any study on Cleaning Up has to either be controlled through the APA and departments of psychology, or explain why it isnt the domain of psychology. At this point enter the pharmaceutical industry and a vested interest against “cleaning up” their customers